Tasigna Side Effects Liver

Some side effects are more severe including swelling in the hands and feet rapid weight gain painful urination severe stomach pain high blood sugar and liver disease.

Tasigna side effects liver.

Tasigna nilotinib side effects range from nausea diarrhea and headaches to cardiovascular problems and irregular rhythms that may lead to sudden death. The most frequently reported side effects included nausea rash headache fatigue pruritus vomiting diarrhea cough constipation arthralgia nasopharyngitis pyrexia night sweats and myelosuppression e g thrombocytopenia neutropenia and anemia. Prolonged qt interval on ekg. Increased or reduced thyroid function.

If you already have liver damage or you re affected by liver damage while taking tasigna you have an increased risk of serious. Skin rash itching headache nausea fatigue tiredness joint or muscle aches or pain back pain diarrhea constipation temporary hair loss or. Tasigna may result in hepatotoxicity as measured by elevations in bilirubin aspartate aminotransferase ast alanine aminotransferase alt and alkaline phosphatase. Tasigna can cause serious side effects that can even lead to death.

These tests will check your heart blood cells white blood cells red blood cells and platelets electrolytes potassium magnesium cholesterol blood sugar and pancreas and liver function. From 2007 to september 30 2019 americans reported 16 478 cases of adverse events related to tasigna according to the fda adverse events reporting system faers. Low levels of a type of white blood cell called neutrophils. Tell your doctor if you have serious side effects of tasigna including.

If experienced these tend to have a. Low levels of white blood cells. Important safety information about tasigna nilotinib capsules. Grade 3 4 elevations of bilirubin ast and alt were reported at a higher frequency in pediatric than in adult patients.

Low amount of sodium in the blood. Atherosclerosis is a serious side effect associated with tasigna use. Drug interactions of tasigna include several drugs that reduce its break down by the liver such as amiodarone disopyramide procainamide quinidine and sotalol because the blood concentration of tasigna may be increased which may increase the occurrence of adverse effects. Qtc prolongation causes an irregular heartbeat which may lead to sudden death.

Qtc prolongation and sudden death. During treatment with tasigna your doctor will do tests to check for side effects. Tasigna can cause qtc prolongation a possibly life threatening heart problem. Cold symptoms stuffy nose sneezing cough or sore throat.