Tablet Capping And Lamination

Although the method is widely used there are still significant challenges with achieving a high quality compact.

Tablet capping and lamination.

Lamination is whenever tablet is breaking or separating anywhere rather than top if is separating from top it is capping. Fines are small dust particles which. Machine related in this article we will be discussing five major causes of this problem and remedies for them. The following are some of the common factors which can cause tablet capping.

Before rectifying be sure it is lamination where is the problem surface of tablet below the top layer or bottom of tablet. Lamination is also caused by the presence of a large amount of fines in the granulations. Capping or lamination is an unsolved common problem in tablet manufacturing. This is the problem faced in the formulation of the granules.

This challenge can be overcome by doing a pre compression as well as reducing the compression and minimizing the tableting rate. Tablet capping and lamination powder compaction is widely used to produce pharmaceutical tablets and is referred to as a tabletting process. Abstract air entrapment efficiency of the powders is one of the main factors leading to occurrence of capping or lamination tendency of tablets manufactured from the directly compressible powder blends. Using acetaminophen containing formulations we examined the potential use of a compaction simulator as a material sparing tool to predict capping occurrence under commercial.